Anti-Decorin Monoclonal Antibody(Clone: DCN/3523)
Product Sizes
20 µg
£397.00
36-2159-20UG
100 µg
£716.00
36-2159-100UG
About this Product
- SKU:
- 36-2159
- Additional Names:
- Bone proteoglycan II; CSCD; Dermatan sulphate proteoglycans II (DSPG2); PG40; PGII; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B
- translate.label.attr.clone:
- DCN/3523
- Clonality:
- Monoclonal
- Extra Details:
- Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation; flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I; II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors; intercellular matrix molecules; such as Fibronectin and Thrombospondin; and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF-alphaand is a direct or indirect negative modulator of TGF-alphasynthesis. Inhibition of Decorin core protein gene expression by the combination of IFN- and TNF may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. The human Decorin gene maps to chromosome 12q21.33 and encodes a 359 amino acid protein.
- Host:
- Mouse
- Immunogen:
- Recombinant human Decorin protein fragment (aa212-336) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
