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Antibodies

Anti-Drebrin 1 (DBN1) Monoclonal Antibody(Clone: DBN1/2880)

Product Sizes
20 µg
£397.00
36-2157-20UG
100 µg
£716.00
36-2157-100UG
About this Product
SKU:
36-2157
Additional Names:
Developmentally regulated brain protein; Drebrin 1; Drebrin; Drebrin E; Drebrin E2; Drebrin1; DrebrinE
translate.label.attr.clone:
DBN1/2880
Clonality:
Monoclonal
Extra Details:
Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration; extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2); and an adult type (A); generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle; heart; placenta; pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
Host:
Mouse
Immunogen:
Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Formalin-fixed; paraffin-embedded human Cervix stained with Drebrin-1 Mouse Monoclonal Antibody (DBN1/2880).
Fig. 3: SDS-PAGE Analysis Purified Drebrin-1 Mouse Monoclonal Antibody (DBN1/2880). Confirmation of Purity and Integrity of Antibody
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using Drebrin-1 Mouse Monoclonal Antibody (DBN1/2880). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using Drebrin-1 Mouse Monoclonal Antibody (DBN1/2880). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that