Anti-BTLA Monoclonal Antibody(Clone: BTLA/1528)
Product Sizes
20 µg
£397.00
36-2151-20UG
100 µg
£716.00
36-2151-100UG
About this Product
- SKU:
- 36-2151
- Additional Names:
- B and T lymphocyte associated protein; B and T lymphocyte attenuator; B and T lymphocyte associated; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA; BTLA_HUMAN; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743
- translate.label.attr.clone:
- BTLA/1528
- Clonality:
- Monoclonal
- Extra Details:
- B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1; all of which are coinhibitory receptors belonging to the CD28 family. However; unlike CTLA-4 and PD-1; BTLA does not interact with B7-Ig family counter receptors. Rather; the herpesvirus entry mediator (HVEM); a TNF receptor; acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals throµgh BTLA. The BTLAHVEM interaction is conserved between Mouse and human; sµggesting that this system is an important pathway regulating lymphocyte activation.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human BTLA protein
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
