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Antibodies

Anti-Cathepsin K (Marker of Tumor Invasiveness) Monoclonal Antibody(Clone: CTSK/2792)

Product Sizes
20 µg
£397.00
36-2149-20UG
100 µg
£716.00
36-2149-100UG
About this Product
SKU:
36-2149
Additional Names:
Cathepsin K; Cathepsin O; Cathepsin O1; Cathepsin O2; Cathepsin X; CTS02; Ctsk; CTSO1; CTSO2; PKND; PYCD
translate.label.attr.clone:
CTSK/2792
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein; which is a member of the peptidase C1 protein family; is predominantly expressed in osteoclasts. However; the encoded protein is also expressed in a significant fraction of human breast cancers; where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis; an autosomal recessive disease characterized by osteosclerosis and short stature.
Host:
Mouse
Immunogen:
Recombinant fragment of human Cathepsin K protein (around aa 163-274) (exact sequence is proprietary)
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Formalin-fixed; paraffin-embedded human Liver stained with Cathepsin K Mouse Monoclonal Antibody (CTSK/2792).
Fig. 3: Analysis of Protein Array containing more than 19;000 full-length human proteins using Cathepsin K Mouse Monoclonal Antibody (CTSK/2792) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals g
Fig. 3: Analysis of Protein Array containing more than 19;000 full-length human proteins using Cathepsin K Mouse Monoclonal Antibody (CTSK/2792) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals g