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Antibodies

Anti-Cathepsin D (Tumor Marker) Monoclonal Antibody(Clone: CTSD/3276)

Product Sizes
20 µg
£397.00
36-2147-20UG
100 µg
£716.00
36-2147-100UG
About this Product
SKU:
36-2147
Additional Names:
CatD; Cathepsin D; Ceroid lipofuscinosis neuronal 10; CLN10; CPSD; Epididymis secretory sperm binding protein Li 130P; Lysosomal aspartyl peptidase; Lysosomal aspartyl protease
translate.label.attr.clone:
CTSD/3276
Clonality:
Monoclonal
Extra Details:
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43kDa preprocathepsin D that is cleaved and glycosylated to form a 46kDa procathepsin D and then further cleaved to produce 28kDa and 15kDa subunits (heavy and light chains; respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases; including breast cancer and possibly Alzheimer's disease.
Host:
Mouse
Immunogen:
Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
Isotype:
Mouse IgG2b; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: SDS-PAGE Analysis Purified Cathepsin D Mouse Monoclonal Antibody (CTSD/3276). Confirmation of Integrity and Purity of Antibody
Fig. 3: Analysis of Protein Array containing more than 19;000 full-length human proteins using Cathepsin D Mouse Monoclonal Antibody (CTSD/3276) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that
Fig. 3: Analysis of Protein Array containing more than 19;000 full-length human proteins using Cathepsin D Mouse Monoclonal Antibody (CTSD/3276) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that