Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Monoclonal Antibody(Clone: rCR2/1952)

Product Sizes

20 µg

£397.00

36-2113-20UG

100 µg

£716.00

36-2113-100UG

About this Product

SKU:: 36-2113
Additional Names:: CD21; Complement C3d receptor (C3DR); Complement Receptor type 2 (CR2); CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9
translate.label.attr.clone:: rCR2/1952
Clonality:: Monoclonal
Extra Details:: Recognizes a protein of 140kDa; which is identified as the complement receptor 2(CR2)/CD21. This protein is expressed strongly on mature B cells; follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny; CD21 appears after the pre-B-stage; is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro.CD21 functions as receptor for C3d; C3dg and iC3b Complement components; for EBV and for IFNalpha.CD21 binds to CD23 and associates with CD19; CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
Host:: Mouse
Immunogen:: Recombinant fragment (around aa 44-196) of human CR2 (CD21) protein (exact sequence is proprietary)
Isotype:: Mouse IgG1; kappa
Reactivities:: Human
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:: Abeomics
Type:: Antibodies:Monoclonal Antibody

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