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Antibodies

Anti-Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker) Monoclonal Antibody(Clone: CPA1/2713)

Product Sizes
20 µg
£397.00
36-2109-20UG
100 µg
£716.00
36-2109-100UG
About this Product
SKU:
36-2109
Additional Names:
Carboxypeptidase A1 (pancreatic); CPA1; Pancreatic Carboxypeptidase A1; Procarboxypeptidase A1 pancreatic
translate.label.attr.clone:
CPA1/2713
Clonality:
Monoclonal
Extra Details:
Human pancreatic procarboxypeptidase A exists as three different active forms; two of which are designated carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). CPA1; also known as CPA; is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase; CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins; thereby playing a key role in protein digestion and degradation. Via its catalytic activity; CPA1 is also thoµght to be involved in zymogen (proenzyme) inhibition; probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer; sµggesting a possible role in either tumor progression or tumor suppression events.
Host:
Mouse
Immunogen:
Recombinant full-length human CPA1 protein
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: SDS-PAGE Analysis of Purified Carboxypeptidase A1 / CPA1 Mouse Monoclonal Antibody (CPA1/2713). Confirmation of Purity and Integrity of Antibody.
Fig. 3: Analysis of Protein Array containing more than 19;000 full-length human proteins using Carboxypeptidase A1 / CPA1 Mouse Monoclonal Antibody (CPA1/2713). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value
Fig. 3: Analysis of Protein Array containing more than 19;000 full-length human proteins using Carboxypeptidase A1 / CPA1 Mouse Monoclonal Antibody (CPA1/2713). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value