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Antibodies

Anti-Calponin-1 (Smooth Muscle Marker) Monoclonal Antibody(Clone: CNN1/1408R)

Product Sizes
20 µg
£397.00
36-2104-20UG
100 µg
£716.00
36-2104-100UG
About this Product
SKU:
36-2104
Additional Names:
Calponin 1 basic smooth muscle; Calponin H1 smooth muscle; Calponin-1; CNN1; Cnn1; Sm Calp; SMCC
translate.label.attr.clone:
CNN1/1408R
Clonality:
Monoclonal
Extra Details:
Multiple isoelectric variants of calponin have been identified; however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form; I-calponin; is primarily restricted to muscle of the urogenital tract; whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting; this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin; F-actin and tropomyosin binding protein; which is thoµght to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Host:
Rabbit
Immunogen:
Recombinant human full-length CNN1 protein
Isotype:
Rabbit IgG
Reactivities:
Human, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Formalin-fixed; paraffin-embedded Rat Uterus stained with Calponin Rabbit Recombinant Monoclonal Antibody (CNN1/1408R).
Fig. 3: SDS-PAGE Analysis of Purified Calponin Rabbit Recombinant Monoclonal Antibody (CNN1/1408R).
Fig. 4: Flow Cytometric Analysis of PFA-fixed K562 cells using Calponin Rabbit Recombinant MAb(CNN1/1408R) followed by Goat anti-Rabbit- IgG-CF488 (Blue); Isotype Control (Red).
Fig. 4: Flow Cytometric Analysis of PFA-fixed K562 cells using Calponin Rabbit Recombinant MAb(CNN1/1408R) followed by Goat anti-Rabbit- IgG-CF488 (Blue); Isotype Control (Red).
Fig. 5: Immunofluorescence Analysis of Human K562 cells labeling CD71 with Calponin Rabbit Recombinant Monoclonal Antibody (CNN1/1408R)followed by Goat anti-rabbit IgG-CF488 (Green). The nuclear counterstain is Reddot (Red)