Anti-Calponin-1 (Smooth Muscle Marker) Monoclonal Antibody (Clone: rCNN1/832)
Product Sizes
20 µg
£397.00
36-2103-20UG
100 µg
£716.00
36-2103-100UG
About this Product
- SKU:
- 36-2103
- Additional Names:
- Calponin 1 basic smooth muscle; Calponin H1 smooth muscle; Calponin-1; CNN1; Cnn1; Sm Calp; SMCC
- translate.label.attr.clone:
- rCNN1/832
- Clonality:
- Monoclonal
- Extra Details:
- Multiple isoelectric variants of calponin have been identified; however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form; I-calponin; is primarily restricted to muscle of the urogenital tract; whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting; this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin; F-actin and tropomyosin binding protein; which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CNN1 protein
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
