Anti-Topoisomerase I; Mitochondrial (TOP1MT) Monoclonal Antibody (Clone: TOP1MT/2883R)
Product Sizes
20 µg
£397.00
36-2089-20UG
100 µg
£716.00
36-2089-100UG
About this Product
- SKU:
- 36-2089
- Additional Names:
- DNA topoisomerase I; TOP1MT; Topoisomerase I mitochondrial; Type IB Topoisomerase
- translate.label.attr.clone:
- TOP1MT/2883R
- Clonality:
- Monoclonal
- Extra Details:
- DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication; recombination; and transcription; DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I; mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase; mitochondrial Topo I requires a divalent metal; either; calcium or magnesium; as well as an alkaline pH for optimal activity.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human TOP1MT protein
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
