Anti-GPN1 / XAB1 (DNA Repair & Protein Synthesis) Monoclonal Antibody (Clone: GPN1/2350)
Product Sizes
20 µg
£397.00
36-2083-20UG
100 µg
£716.00
36-2083-100UG
About this Product
- SKU:
- 36-2083
- Additional Names:
- ATP(GTP) binding protein (ATPBD1A); GPN-loop GTPase 1; GPN1; MBD2-interacting protein (MBDin); NTPBP; RNA polymerase II associated protein 4 (RPAP4); XPA-binding protein 1 (XAB1) GTPase
- translate.label.attr.clone:
- GPN1/2350
- Clonality:
- Monoclonal
- Extra Details:
- GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms); thereby forming an interface with Poll II. Via this interaction; GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition; GPN1 interacts with components of the integrator and molecular chaperone complexes; further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region; suggesting that GPN1 has possible GTPase activity.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human GPN1 protein
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
