Anti-CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Monoclonal Antibody (Clone: CFTR/1785)
Product Sizes
20 µg
£397.00
36-2048-20UG
100 µg
£716.00
36-2048-100UG
About this Product
- SKU:
- 36-2048
- Additional Names:
- ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7); cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
- translate.label.attr.clone:
- CFTR/1785
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 165-170kDa; identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD); two nucleotide-binding domains (NBD); and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters; also known as traffic ATPases; which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3';5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas; airway; intestine; bile duct; sweat gland; and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 258-385) of human CFTR protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
