Anti-Ksp-Cadherin / CDH16 (Renal Cell Marker) Monoclonal Antibody (Clone: CDH16/2125)
Product Sizes
20 µg
£397.00
36-2010-20UG
100 µg
£716.00
36-2010-100UG
About this Product
- SKU:
- 36-2010
- Additional Names:
- Cadherin-16 (CDH16); Kidney-specific cadherin; Ksp-cadherin antibody
- translate.label.attr.clone:
- CDH16/2125
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a protein of 130kDa; identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis; tissue morphogenesis; tissue structure maintenance; cell polarization; neoplastic invasiveness and metastasis; and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney; Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells; and not in glomeruli; renal interstitial cells; or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 371-507) of human CDH16 protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
