Monoclonal Antibody to CD79a (B-Cell Marker)(Clone : JCB117)
Product Sizes
100 µg
£716.00
36-1978-100UG
About this Product
- SKU:
- 36-1978
- Additional Names:
- CD79A||IGA||MB1
- translate.label.attr.clone:
- JCB117
- Clonality:
- Monoclonal
- Extra Details:
- A disulphide-linked heterodimer; consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides; is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage; early in maturation; and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type; in B cell lines; B cell lymphomas; and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20; but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein.
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
