Monoclonal Antibody to CD63 (Late Endosomes Marker)(Clone : MX-49.129.5)
Product Sizes
100 µg
£716.00
36-1960-100UG
About this Product
- SKU:
- 36-1960
- Additional Names:
- CD63||MLA1||TSPAN30
- translate.label.attr.clone:
- MX-49.129.5
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes protein of 26kDa-60kDa; which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets; monocytes and macrophages; and is weakly expressed on granulocytes; T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9; CD37 and CD53; which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Full length CD63 of human origin
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
