Monoclonal Antibody to CD37 (Peripheral Mature B-Cell Marker)(Clone : IPO-24)
Product Sizes
100 µg
£716.00
36-1935-100UG
About this Product
- SKU:
- 36-1935
- Additional Names:
- CD37||TSPAN26
- translate.label.attr.clone:
- IPO-24
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 33-55kDa; identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny; CD37 appears after the pre-B-cell stage; is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present; at low densities; on resting and activated T cells; neutrophils; monocytes; and some myelomonocytic leukemia cells. It is absent from platelets; erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins; including CD9; CD53; CD63; CD81; and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL); hairy cell leukemia (HCL); and all types of B-cell non-Hodgkin&' lymphoma (B-NHL).
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Spleen cells of a patient with hairy cell leukemia
- Isotype:
- Mouse IgG2b; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:cd37a.png
