Monoclonal Antibody to CD36 (Platelet & Microvessel Marker)(Clone : GPIIIb/654)
Product Sizes
100 µg
£716.00
36-1934-100UG
About this Product
- SKU:
- 36-1934
- Additional Names:
- CD36||GP3B||GP4
- translate.label.attr.clone:
- GPIIIb/654
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 80kDa-90kDa; identified as CD36. It is expressed on platelets; monocytes and macrophages; microvascular endothelial cells; erythrocyte precursors; mammary epithelial cells; and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP); collagen types I; IV and V; P. falciparum malaria-infected erythrocytes; and sickle erythrocytes. It also functions as a scavenger receptor; mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation; macrophage foam cell development; inflammation; and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human GPIIIb protein
- Isotype:
- Mouse IgG2a; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
