Monoclonal Antibody to CD86 (Dendritic Cells Maturation Marker)(Clone : SPM600)
Product Sizes
100 µg
£716.00
36-1909-100UG
About this Product
- SKU:
- 36-1909
- Additional Names:
- CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1
- translate.label.attr.clone:
- SPM600
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 70kDa; which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86; along with CD80/B71; is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction; it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human full-length CD86 protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
