Monoclonal Antibody to CD86 (Dendritic Cells Maturation Marker)(Clone : C86/1146)

Product Sizes

100 µg

£716.00

36-1908-100UG

About this Product

SKU:: 36-1908
Additional Names:: CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1
translate.label.attr.clone:: C86/1146
Clonality:: Monoclonal
Extra Details:: Recognizes a protein of 70kDa; which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86; along with CD80/B71; is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction; it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Format:: Purified
Host:: Mouse
Immunogen:: Recombinant human full-length CD86 protein
Isotype:: Mouse IgG1; kappa
Purification:: Affinity Chromatography
Reactivities:: Human, Mouse, Rat
Shipping Conditions:: Blue Ice
Storage Conditions:: Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:: Abeomics
Type:: Antibodies:Monoclonal Antibody

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