Monoclonal Antibody to CD22 / BL-CAM(Clone : MYG13)
Product Sizes
100 µg
£716.00
36-1898-100UG
About this Product
- SKU:
- 36-1898
- Additional Names:
- CD22||SIGLEC2
- translate.label.attr.clone:
- MYG13
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 130-140kDa; identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny; CD22 is first expressed in the cytoplasm of pro-B and pre-B cells; and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells; CD22 is found highly expressed in follicular mantle and marginal zone B-cells; and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human Raji cells
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
