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Antibodies

Monoclonal Antibody to CD8B (Cytotoxic / Suppressor T-Cell Marker)(Clone : BU88)

Product Sizes
100 µg
£716.00
36-1880-100UG
About this Product
SKU:
36-1880
Additional Names:
CD8B||CD8B1
translate.label.attr.clone:
BU88
Clonality:
Monoclonal
Extra Details:
The T cell receptor (TCR) is a heterodimer composed of chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8); a cell surface glycoprotein; is a two chain complex receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Format:
Purified
Host:
Mouse
Immunogen:
Human CD8 beta
Isotype:
Mouse IgG1; kappa
Purification:
Affinity Chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody