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Antibodies

Monoclonal Antibody to CD5 (Mantle Cell Lymphoma Marker)(Clone : SPM546)

Product Sizes
100 µg
£716.00
36-1858-100UG
About this Product
SKU:
36-1858
Additional Names:
CD5||LEU1
translate.label.attr.clone:
SPM546
Clonality:
Monoclonal
Extra Details:
Recognizes a 67kDa transmembrane protein; which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes; the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells; e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL); mantle cell lymphoma; and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers; especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition; anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
Format:
Purified
Host:
Mouse
Immunogen:
Human CD5 recombinant protein
Isotype:
Mouse IgG1; kappa
Purification:
Affinity Chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg