Monoclonal Antibody to Renal Cell Carcinoma / gp200(Clone : SPM487)
Product Sizes
100 µg
£716.00
36-1817-100UG
About this Product
- SKU:
- 36-1817
- Additional Names:
- CA9||G250||MN
- translate.label.attr.clone:
- SPM487
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a glycoprotein of ~200kDa; identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants; such as the Lewis blood group antigens; epithelial membrane antigen; HMFG; and AB blood group antigens. In normal kidney; gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule; as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly; gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Microsomal fraction of human renal cortical tissue homogenate
- Isotype:
- Mouse IgG2b; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
