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Antibodies

Monoclonal Antibody to Vimentin (Mesenchymal Cell Marker)(Clone : SPM576)

Product Sizes
100 µg
£716.00
36-1800-100UG
About this Product
SKU:
36-1800
Additional Names:
VIM
translate.label.attr.clone:
SPM576
Clonality:
Monoclonal
Extra Details:
This MAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP's) such as desmin; keratin; neurofilament; and glial fibrillary acid protein. Anti-vimentin alone is of limited value as a diagnostic tool; however; when used in panels with other antibodies; it is useful for the sub-classification of a given tumor. Expression of vimentin; when used in conjunction with anti-keratin; is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells; including melanocytes; lymphocytes; endothelial cells; and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity; since there are a few tumors that do not contain vimentin; e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.
Format:
Purified
Host:
Mouse
Immunogen:
Human vimentin recombinant protein
Isotype:
Mouse IgG1; kappa
Purification:
Affinity Chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg