Monoclonal Antibody to SUMO-1(Clone : SPM571)
Product Sizes
100 µg
£716.00
36-1786-100UG
About this Product
- SKU:
- 36-1786
- Additional Names:
- SUMO1||SMT3C||SMT3H3||UBL1||OK/SW-cl.43
- translate.label.attr.clone:
- SPM571
- Clonality:
- Monoclonal
- Extra Details:
- This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins; which include SUMO-1; SUMO-2 and SUMO-3; belong to the ubiquitin-like protein family. Like ubiquitin; the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also; both utilize the E1; E2; and E3 cascade enzymes for conjugation. However; SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation; whereas sumoylation targets proteins to a variety of cellular processing; including nuclear transport; transcriptional regulation; apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human SUMO1 protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
