Monoclonal Antibody to CD284 (Toll-Like Receptor 4)(Clone : TLR4/230)
Product Sizes
100 µg
£716.00
36-1744-100UG
About this Product
- SKU:
- 36-1744
- Additional Names:
- TLR4
- translate.label.attr.clone:
- TLR4/230
- Clonality:
- Monoclonal
- Extra Details:
- This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family; which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents; and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human TLR4 protein
- Isotype:
- Mouse IgG2a
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
