Monoclonal Antibody to TTF-1 / NKX2.1 (Thyroid & Lung Epithelial Marker)(8G7G3/1 + NX2.1/690)
Product Sizes
100 µg
£716.00
36-1742-100UG
About this Product
- SKU:
- 36-1742
- Additional Names:
- NKX2-1||NKX2A||TITF1||TTF1
- translate.label.attr.clone:
- 8G7G3/1 + NX2.1/690
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 40kDa; identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver; stomach; pancreas; small intestine; colon; kidney; breast; skin; testes; pituitary; prostate; and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast; mediastinal germ cell tumors; and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Rat full length TTF-1 recombinant protein (8G7G3/1); Recombinant TTF-1 protein (NX2.1/690)
- Isotype:
- Mouse IgG1; kappa + Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
