Polyclonal Antibody to TIMP-3 (Tissue Inhibitor of Metalloproteinase-3)
Product Sizes
100 µg
£716.00
36-1738-100UG
About this Product
- SKU:
- 36-1738
- Additional Names:
- TIMP3
- Clonality:
- Polyclonal
- Extra Details:
- TIMP3 (tissue inhibitor of metalloproteinases 3); along with family members TIMP1; TIMP2; and TIMP4; are inhibitors of the matrix metalloproteinases (MMPs); a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia; and in the formation; branching and expansion of epithelial tubes.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- The amino acid sequence (aa175-211); used as the immunogen for TIMP3 Ab; is 100% homologous in human; cow; dog and horse; and 94% homologous in mouse and Rat.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
