Monoclonal Antibody to Macrophage L1 Protein(Clone : MAC387)
Product Sizes
100 µg
£716.00
36-1665-100UG
About this Product
- SKU:
- 36-1665
- Additional Names:
- S100A8||CAGA||CFAG||MRP8
- translate.label.attr.clone:
- MAC387
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes the L1 or Calprotectin molecule; an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain expressed by granulocytes; monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues; the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes); liver (Kupffer's cells); lung (alveolar macrophages); lymph nodes (free and fixed macrophages); spleen (free and fixed macrophages); bone marrow (fixed macrophages); serous fluids (pleural and peritoneal macrophages); skin (histiocytes; Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system; recognizing; engulfing and destroying many potential pathogens including bacteria; pathogenic protozoa; fungi and helminthes. This MAb reacts with neutrophils; monocytes; macrophages; and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Affinity purified monocyte membrane prepaRation
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
