Monoclonal Antibody to Bcl-2 (Apoptosis & Follicular Lymphoma Marker)(Clone : SPM117)
Product Sizes
100 µg
£716.00
36-1640-100UG
About this Product
- SKU:
- 36-1640
- Additional Names:
- BCL2
- translate.label.attr.clone:
- SPM117
- Clonality:
- Monoclonal
- Extra Details:
- This antibody recognizes a protein of 25-26kDa; identified as the bcl-2 α oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas; neoplastic germinal centers express high levels of bcl-2 α protein; whereas the normal or hyperplastic germinal centers are negative. Consequently; this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- A synthetic peptide; aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein.
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
