Monoclonal Antibody to Cyclin D1 (G1-Cyclin & Mantle Cell Marker)(Clone : SPM587)
Product Sizes
100 µg
£716.00
36-1635-100UG
About this Product
- SKU:
- 36-1635
- Additional Names:
- CCND1||BCL1||PRAD1
- translate.label.attr.clone:
- SPM587
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 36kDa; identified as cyclin D1. Cyclin D1; one of the key cell cycle regulators; is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally; hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human recombinant full length cyclin D1 protein
- Isotype:
- Mouse IgG2a; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
