Monoclonal Antibody to CD45 / LCA (Leucocyte Marker)(2B11 + PD7/26)
Product Sizes
100 µg
£716.00
36-1619-100UG
About this Product
- SKU:
- 36-1619
- Additional Names:
- PTPRC||CD45
- translate.label.attr.clone:
- 2B11 + PD7/26
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220; 205; 190; 180kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines; normal and malignant non-hematopoietic tissues. The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. A positive result with this MAb is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma; some T-cell lymphomas; and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Isolated neoplastic cells from T cell lymphoma (2B11); and human peripheral blood lymphocytes maintained in T cell growth factor (PD7/26)
- Isotype:
- Mouse IgG1; kappa + Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
