Monoclonal Antibody to CD45 / LCA (Leucocyte Marker)(Clone : 2B11)
Product Sizes
20 µg
£397.00
36-1615-20UG
100 µg
£716.00
36-1615-100UG
About this Product
- SKU:
- 36-1615
- Additional Names:
- PTPRC||CD45
- translate.label.attr.clone:
- 2B11
- Clonality:
- Monoclonal
- Extra Details:
- CD45R; also designated CD45 and PTPRC; has been identified as a transmembrane glycoprotein; broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4; 5; and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4); CD45RB (exon 5); CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R; while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Isolated neoplastic cells from T cell lymphoma
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
