Monoclonal Antibody to CD45RA (Leucocyte Marker)(Clone : PTPRC/1148)
Product Sizes
100 µg
£716.00
36-1610-100UG
About this Product
- SKU:
- 36-1610
- Additional Names:
- PTPRC||CD45
- translate.label.attr.clone:
- PTPRC/1148
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 205kDa-220kDa; identified as CD45RA. It is an isoform of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A; B and C; respectively. The differential splicing of the exons generates at least five isoforms; ABC; AB; BC; B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells; 50% of peripheral CD8+ T-cells; B-cells; and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary; predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD45RA protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
