Monoclonal Antibody to Parathyroid Hormone (PTH) (C-Terminal)(Clone : PTH/1175)
Product Sizes
100 µg
£716.00
36-1600-100UG
About this Product
- SKU:
- 36-1600
- Additional Names:
- PTH
- translate.label.attr.clone:
- PTH/1175
- Clonality:
- Monoclonal
- Extra Details:
- Epitope of this MAb maps in the C-terminus of PTH; a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.?It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation; as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures; tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (84 amino acid residues from C-terminus) of human PTH protein
- Isotype:
- Mouse IgG2b; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
