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Antibodies

Monoclonal Antibody to Beta-2 Microglobulin (Renal Failure & Tumor Marker)(Clone : SPM617)

Product Sizes
100 µg
£716.00
36-1590-100UG
About this Product
SKU:
36-1590
Additional Names:
B2M||CDABP0092||HDCMA22P
translate.label.attr.clone:
SPM617
Clonality:
Monoclonal
Extra Details:
Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever; inflammation; and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine; increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS; malignant monoclonal plasma cell dyscrasia; solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency; graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
Format:
Purified
Host:
Mouse
Immunogen:
Full length recombinant human B2M protein
Isotype:
Mouse IgG1; kappa
Purification:
Affinity Chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody