Monoclonal Antibody to UACA / Nucling (Nuclear Membrane Marker)(Clone : UACA/1222)
Product Sizes
100 µg
£716.00
36-1578-100UG
About this Product
- SKU:
- 36-1578
- Additional Names:
- UACA||KIAA1561
- translate.label.attr.clone:
- UACA/1222
- Clonality:
- Monoclonal
- Extra Details:
- UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1;416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis; a characteristic of Vogt-Koyanagi-Harada disease; and in patients with Graves' disease. UACA was also later identified as Nucling; an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human UACA protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
