Monoclonal Antibody to PAX6 (Stem Cell Marker)(Clone : SPM612)
Product Sizes
100 µg
£716.00
36-1529-100UG
About this Product
- SKU:
- 36-1529
- Additional Names:
- PAX6||AN2
- translate.label.attr.clone:
- SPM612
- Clonality:
- Monoclonal
- Extra Details:
- Pax genes contain paired domains with strong homology to genes in Drosophila; which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia; a congenital malformation of the eye; chiefly characterized by iris hypoplasia; which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia; such as Peters anomaly; a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains; the amino-terminal subdomain and the carboxy-terminal subdomain; which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
