Monoclonal Antibody to Neurofilament; phospho (NF-H) (Neuronal Marker)(Clone : NE14)
Product Sizes
100 µg
£716.00
36-1511-100UG
About this Product
- SKU:
- 36-1511
- Additional Names:
- NEFH||KIAA0845||NFH
- translate.label.attr.clone:
- NE14
- Clonality:
- Monoclonal
- Extra Details:
- This MAb reacts with a 200kDa protein; identified as heavy sub-unit of neurofilaments (NF-H). It reacts specifically with the phosphorylated KSP/KEP segment at the C-terminus of the heavy subunit (NF-H) of neurofilaments. After dephosphorylation of neurofilaments with alkaline phosphatase; this Ab no longer binds. Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons; peripheral nerves; and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L); 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural; neuroendocrine; and endocrine tumors. Neuromas; ganglioneuromas; gangliogliomas; ganglioneuroblastomas; and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids; neuroendocrine carcinomas of the skin; and oat cell carcinomas of the lung also express neurofilament.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Crude neurofilament prepaRation from porcine spinal cord
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
