Monoclonal Antibody to MUC3 (Mucin 3)(Clone : SPM200)
Product Sizes
100 µg
£716.00
36-1461-100UG
About this Product
- SKU:
- 36-1461
- Additional Names:
- MUC3A; MUC3
- translate.label.attr.clone:
- SPM200
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a protein of HMW; identified as mucin 3 glycoprotein (MUC3). Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes; MUC1; or MUC2. MUC3 is distributed in colon and rectum; and is also present to a lesser extent in breast; lung and salivary gland tissues. The Mucins are a family of highly glycosylated; secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1); 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- A synthetic peptide of 35 amino acids; SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS); which contains two of the MUC3 tandem repeats; coupled to KLH.
- Isotype:
- Mouse IgG2a; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
