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Antibodies

Monoclonal Antibody to MUC1 / EMA / CD227 (Epithelial Marker)(Clone : SPM132)

Product Sizes
100 µg
£716.00
36-1448-100UG
About this Product
SKU:
36-1448
Additional Names:
MUC1||PUM
translate.label.attr.clone:
SPM132
Clonality:
Monoclonal
Extra Details:
In Western blotting; it recognizes proteins in MW range of 265-400kDa; identified as different glycoforms of EMA. This MAb reacts with the DTRP epitope in the tandem repeats. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain; which is involved in cell signaling; through phosphorylations and protein-protein interactions. In immunohistochemical assays; it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Format:
Purified
Host:
Mouse
Immunogen:
Human milk fat globule membranes
Isotype:
Mouse IgG1; kappa
Purification:
Affinity Chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg