Monoclonal Antibody to CD99 / MIC2 (Ewing's Sarcoma Marker)(Clone : SPM596)
Product Sizes
100 µg
£716.00
36-1431-100UG
About this Product
- SKU:
- 36-1431
- Additional Names:
- CD99||MIC2||MIC2X||MIC2Y
- translate.label.attr.clone:
- SPM596
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a sialoglycoprotein of 27-32kDa; identified as CD99; or MIC2 gene product; or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins; which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32). Although its function is not fully understood; CD99 is implicated in various cellular processes including homotypic aggregation of T cells; upregulation of T cell receptor and MHS molecules; apoptosis of immature thymocytes and leukocyte diapedesis. CD99 is expressed on the cell membrane of some lymphocytes; cortical thymocytes; and granulosa cells of the ovary. Most pancreatic islet cells; Sertoli cells of the testis; and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing s sarcoma cells and primitive peripheral neuroectodermal tumors.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human MIC2 protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
