Monoclonal Antibody to Cytokeratin 14 (KRT14) (Squamous Cell Marker)(Clone : SPM263)
Product Sizes
100 µg
£716.00
36-1367-100UG
About this Product
- SKU:
- 36-1367
- Additional Names:
- KRT14
- translate.label.attr.clone:
- SPM263
- Clonality:
- Monoclonal
- Extra Details:
- Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia; some glandular epithelia; myoepithelium; and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore; this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics; and in identifying metaplastic carcinomas of the breast.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- A synthetic peptide of 15 amino acid from the C-terminus of human keRatin 14.
- Isotype:
- Mouse IgG3; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
