Monoclonal Antibody to HSP27 (Heat Shock Protein 27)(Clone : G3.1)

Product Sizes

100 µg

£716.00

36-1239-100UG

About this Product

SKU:: 36-1239
Additional Names:: HSPB1||HSP27||HSP28
translate.label.attr.clone:: G3.1
Clonality:: Monoclonal
Extra Details:: This MAb reacts specifically with heat shock protein HSP27 in human and monkey tissues and cell lines such as MCF-7. HSP27; also referred to as the Estrogen-Regulated 24K protein and HSP28; is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature; as well as by estrogen in hormone responsive cells. Interestingly; human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian alpha -crystalline lens protein. Because of the estrogen responsive nature of HSP27; this protein has been studied extensively in human estrogen responsive tissues such as cervix; endometrium and breast tissue. Therefore HSP27 may be useful in classifying various hormone sensitive tumors.
Format:: Purified
Host:: Mouse
Immunogen:: Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells.
Isotype:: Mouse IgG1; kappa
Purification:: Affinity Chromatography
Reactivities:: Human, Mouse, Rat
Shipping Conditions:: Blue Ice
Storage Conditions:: Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:: Abeomics
Type:: Antibodies:Monoclonal Antibody

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