Monoclonal Antibody to Histone H1 (Nuclear Marker)(Clone : HH1/957)
Product Sizes
100 µg
£716.00
36-1213-100UG
About this Product
- SKU:
- 36-1213
- translate.label.attr.clone:
- HH1/957
- Clonality:
- Monoclonal
- Extra Details:
- Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A; H2B; H3; and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers; forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1; derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails; but also in their globular domains. Such modifications include methylation; citrullination; acetylation; phosphorylation; sumoylation; ubiquitination and ADP-ribosylation.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human Histone H1 protein
- Isotype:
- Mouse IgG2a; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
