Monoclonal Antibody to Blood Group Antigen A (CD173)(Clone : 3-3A)
Product Sizes
100 µg
£716.00
36-1199-100UG
About this Product
- SKU:
- 36-1199
- Additional Names:
- ABO
- translate.label.attr.clone:
- 3-3A
- Clonality:
- Monoclonal
- Extra Details:
- This MAb preferably reacts with determinants of chain A and H type 3 (Gal1-3GalNAc-R) and 4 (Gal1-3GalNAc-R); but not with type 1 and 2 chain structures. It is not reactive with immuno-dominant A trisaccharide. This MAb is applicable for tissue staining in tumor patients with blood groups A and AB. It shows a highly heterogeneous reactivity in human colon tumor tissue and adjacent mucosa. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A; B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type; and are detected on erythrocytes; certain epithelial cells; and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens; including A; B; H; Lewis A; Lewis B; Lewis X; Lewis Y; and precursor type 1 chain antigens.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Mucin isolated from an ovarian cyst fluid
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
