Monoclonal Antibody to AMP Deaminase; Isoform E (AMPD3) (Erythroid Marker)(Clone : AMPD3/901)
Product Sizes
100 µg
£716.00
36-1185-100UG
About this Product
- SKU:
- 36-1185
- Additional Names:
- AMPD3
- translate.label.attr.clone:
- AMPD3/901
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a protein of ~90kDa; which is identified as Adenosine Monophosphate Deaminase; isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate; a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms; whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood; bone marrow; and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia; identification of bone marrow erythroid precursors; gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human AMDP3 protein
- Isotype:
- Mouse IgG2b; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
