Monoclonal Antibody to Alkaline Phosphatase (Placental) / PLAP (Germ Cell Tumor Marker)(Clone : PL8-F6)
Product Sizes
100 µg
£716.00
36-1158-100UG
About this Product
- SKU:
- 36-1158
- Additional Names:
- ALPP||PLAP
- translate.label.attr.clone:
- PL8-F6
- Clonality:
- Monoclonal
- Extra Details:
- Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast; gastrointestinal; prostatic; and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive; but they regularly fail to stain with anti-EMA; whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Purified human PLAP protein
- Isotype:
- Mouse IgG2b; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
