Monoclonal Antibody to TRIM29 (Lung Squamous Cell Carcinoma Marker)(Clone : TRIM29/1042)
Product Sizes
100 µg
£716.00
36-1147-100UG
About this Product
- SKU:
- 36-1147
- Additional Names:
- TRIM29||ATDC
- translate.label.attr.clone:
- TRIM29/1042
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a 66kDa protein; which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin; a substrate for the PKC family of protein kinases; and with hPKCI-1; an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs; suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer; and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy; when used in a panel with TTF-1; p63; CK5/6; and Napsin-A antibodies.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein
- Isotype:
- Mouse IgG2b; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
