Monoclonal Antibody to CA19-9 / Sialyl Lewisa (GI Tumor Marker)(Clone : SPM588)
Product Sizes
100 µg
£716.00
36-11044-100UG
About this Product
- SKU:
- 36-11044
- translate.label.attr.clone:
- SPM588
- Clonality:
- Monoclonal
- Extra Details:
- CA19-9; a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein; is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues; sialyl Lewisa antigen is present in ductal epithelium of the breast; kidney; salivary gland; and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas; including adenocarcinomas of the stomach; intestine; and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially; CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is superb for staining of formalin-fixed; paraffin-embedded tissues.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B- patient (0Le).
- Isotype:
- Mouse IgM; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
